Gene Review:
MLYCD - malonyl-CoA decarboxylase
Homo sapiens
Synonyms:
MCD, Malonyl-CoA decarboxylase, mitochondrial, hMCD
Eaton,
Fukumoto,
Stefanutti,
Spitz,
Zammit,
Pierro,
de Wit,
de Coo,
Verbeek,
Schot,
Schoonderwoerd,
Duran,
de Klerk,
Huijmans,
Lequin,
Verheijen,
Mancini,
FitzPatrick,
Hill,
Tolmie,
Thorburn,
Christodoulou,
Santer,
Fingerhut,
Lässker,
Wightman,
Fitzpatrick,
Olgemöller,
Roscher,
- Cloning and mutational analysis of human malonyl-coenzyme A decarboxylase. Gao, J., Waber, L., Bennett, M.J., Gibson, K.M., Cohen, J.C. J. Lipid Res. (1999)
- MLYCD mutation analysis: evidence for protein mistargeting as a cause of MLYCD deficiency. Wightman, P.J., Santer, R., Ribes, A., Dougherty, F., McGill, N., Thorburn, D.R., FitzPatrick, D.R. Hum. Mutat. (2003)
- Holocarboxylase synthetase is an obligate participant in biotin-mediated regulation of its own expression and of biotin-dependent carboxylases mRNA levels in human cells. Solórzano-Vargas, R.S., Pacheco-Alvarez, D., León-Del-Río, A. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Incidence and clinical significance of multiple consecutive, appropriate, high-energy discharges in patients with implanted cardioverter-defibrillators. Villacastín, J., Almendral, J., Arenal, A., Albertos, J., Ormaetxe, J., Peinado, R., Bueno, H., Merino, J.L., Pastor, A., Medina, O., Tercedor, L., Jiménez, F., Delcán, J.L. Circulation (1996)
- A study of male veterans' beliefs toward domestic violence in a batterers intervention program. Craig, M.E., Robyak, J., Torosian, E.J., Hummer, J. Journal of interpersonal violence. (2006)
- Catalytic defect of medium-chain acyl-coenzyme A dehydrogenase deficiency. Lack of both cofactor responsiveness and biochemical heterogeneity in eight patients. Amendt, B.A., Rhead, W.J. J. Clin. Invest. (1985)
- The molecular basis of malonyl-CoA decarboxylase deficiency. FitzPatrick, D.R., Hill, A., Tolmie, J.L., Thorburn, D.R., Christodoulou, J. Am. J. Hum. Genet. (1999)
- Clustering of mutations in the biotin-binding region of holocarboxylase synthetase in biotin-responsive multiple carboxylase deficiency. Dupuis, L., Leon-Del-Rio, A., Leclerc, D., Campeau, E., Sweetman, L., Saudubray, J.M., Herman, G., Gibson, K.M., Gravel, R.A. Hum. Mol. Genet. (1996)
- Inhibition of erythromycin synthesis by disruption of malonyl-coenzyme A decarboxylase gene eryM in Saccharopolyspora erythraea. Hsieh, Y.J., Kolattukudy, P.E. J. Bacteriol. (1994)
- Biotin-responsive immunoregulatory dysfunction in multiple carboxylase deficiency. Fischer, A., Munnich, A., Saudubray, J.M., Mamas, S., Coudé, F.X., Charpentier, C., Dray, F., Frézal, J., Griscelli, C. J. Clin. Immunol. (1982)
- Serum IgE in primary glomerular diseases and its clinical significance. Shu, K.H., Lian, J.D., Yang, Y.F., Lu, Y.S., Wang, J.Y. Nephron (1988)
- Holocarboxylase synthetase deficiency: report of a case with onset in late infancy. Touma, E., Suormala, T., Baumgartner, E.R., Gerbaka, B., Ogier de Baulny, H., Loiselet, J. J. Inherit. Metab. Dis. (1999)
- MCD encodes peroxisomal and cytoplasmic forms of malonyl-CoA decarboxylase and is mutated in malonyl-CoA decarboxylase deficiency. Sacksteder, K.A., Morrell, J.C., Wanders, R.J., Matalon, R., Gould, S.J. J. Biol. Chem. (1999)
- Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry. Wang, X., Stanley, W.C., Brunengraber, H., Kasumov, T. Anal. Biochem. (2007)
- Autosomal dominant medullary cystic disease: a disorder with variable clinical pictures and exclusion of linkage with the NPH1 locus. Scolari, F., Ghiggeri, G.M., Casari, G., Amoroso, A., Puzzer, D., Caridi, G.L., Valzorio, B., Tardanico, R., Vizzardi, V., Savoldi, S., Viola, B.F., Bossini, N., Prati, E., Gusmano, R., Maiorca, R. Nephrol. Dial. Transplant. (1998)
- Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle. Kuhl, J.E., Ruderman, N.B., Musi, N., Goodyear, L.J., Patti, M.E., Crunkhorn, S., Dronamraju, D., Thorell, A., Nygren, J., Ljungkvist, O., Degerblad, M., Stahle, A., Brismar, T.B., Andersen, K.L., Saha, A.K., Efendic, S., Bavenholm, P.N. Am. J. Physiol. Endocrinol. Metab. (2006)
- Malonyl-CoA decarboxylase in rat brain mitochondria. Kim, Y.S., Kolattukudy, P.E., Boos, A. Int. J. Biochem. (1979)
- Low-temperature magnetic circular dichroism studies of native laccase: spectroscopic evidence for exogenous ligand bridging at a trinuclear copper active site. Allendorf, M.D., Spira, D.J., Solomon, E.I. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells. Mulder, H., Lu, D., Finley, J., An, J., Cohen, J., Antinozzi, P.A., McGarry, J.D., Newgard, C.B. J. Biol. Chem. (2001)
- Expression of genes regulating Malonyl-CoA in human skeletal muscle. Pender, C., Trentadue, A.R., Pories, W.J., Dohm, G.L., Houmard, J.A., Youngren, J.F. J. Cell. Biochem. (2006)
- Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis. Eaton, S., Fukumoto, K., Stefanutti, G., Spitz, L., Zammit, V.A., Pierro, A. Biochem. Soc. Trans. (2003)
- Brain abnormalities in a case of malonyl-CoA decarboxylase deficiency. de Wit, M.C., de Coo, I.F., Verbeek, E., Schot, R., Schoonderwoerd, G.C., Duran, M., de Klerk, J.B., Huijmans, J.G., Lequin, M.H., Verheijen, F.W., Mancini, G.M. Mol. Genet. Metab. (2006)
- Spectroscopic properties and electronic structure of low-spin Fe(III)-alkylperoxo complexes: homolytic cleavage of the O-O bond. Lehnert, N., Ho, R.Y., Que, L., Solomon, E.I. J. Am. Chem. Soc. (2001)
- Tandem mass spectrometric determination of malonylcarnitine: diagnosis and neonatal screening of malonyl-CoA decarboxylase deficiency. Santer, R., Fingerhut, R., Lässker, U., Wightman, P.J., Fitzpatrick, D.R., Olgemöller, B., Roscher, A.A. Clin. Chem. (2003)
- Kinetic, spectroscopic, and structural investigations of the soybean lipoxygenase-1 first-coordination sphere mutant, Asn694Gly. Segraves, E.N., Chruszcz, M., Neidig, M.L., Ruddat, V., Zhou, J., Wecksler, A.T., Minor, W., Solomon, E.I., Holman, T.R. Biochemistry (2006)