Gene Review:
Grk1 - G protein-coupled receptor kinase 1
Mus musculus
Synonyms:
Gprk1, RK, Rhodopsin kinase, Rhok, Rk
- Cooperation of Gq, Gi, and G12/13 in protein kinase D activation and phosphorylation induced by lysophosphatidic acid. Yuan, J., Slice, L.W., Gu, J., Rozengurt, E. J. Biol. Chem. (2003)
- Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis. Moechars, D., Lorent, K., Van Leuven, F. Neuroscience (1999)
- PAG3/Papalpha/KIAA0400, a GTPase-activating protein for ADP-ribosylation factor (ARF), regulates ARF6 in Fcgamma receptor-mediated phagocytosis of macrophages. Uchida, H., Kondo, A., Yoshimura, Y., Mazaki, Y., Sabe, H. J. Exp. Med. (2001)
- The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors. Baehr, W., Karan, S., Maeda, T., Luo, D.G., Li, S., Bronson, J.D., Watt, C.B., Yau, K.W., Frederick, J.M., Palczewski, K. J. Biol. Chem. (2007)
- G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization. Peppel, K., Boekhoff, I., McDonald, P., Breer, H., Caron, M.G., Lefkowitz, R.J. J. Biol. Chem. (1997)
- Photoreceptors of Nrl -/- mice coexpress functional S- and M-cone opsins having distinct inactivation mechanisms. Nikonov, S.S., Daniele, L.L., Zhu, X., Craft, C.M., Swaroop, A., Pugh, E.N. J. Gen. Physiol. (2005)
- Involvement of G protein-coupled receptor kinase (GRK) 3 and GRK2 in down-regulation of the alpha2B-adrenoceptor. Desai, A.N., Salim, S., Standifer, K.M., Eikenburg, D.C. J. Pharmacol. Exp. Ther. (2006)
- GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo. Vroon, A., Heijnen, C.J., Raatgever, R., Touw, I.P., Ploemacher, R.E., Premont, R.T., Kavelaars, A. J. Leukoc. Biol. (2004)
- Altered regulation of cyclic AMP-dependent protein kinase in a mouse lymphoma cell line. Lasser, M., Daniel, V. Biochim. Biophys. Acta (1977)
- Light-dependent redistribution of visual arrestins and transducin subunits in mice with defective phototransduction. Zhang, H., Huang, W., Zhang, H., Zhu, X., Craft, C.M., Baehr, W., Chen, C.K. Mol. Vis. (2003)
- Agonist activated adrenocorticotropin receptor internalizes via a clathrin-mediated G protein receptor kinase dependent mechanism. Baig, A.H., Swords, F.M., Szaszák, M., King, P.J., Hunyady, L., Clark, A.J. Endocr. Res. (2002)
- G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice. Bohn, L.M., Gainetdinov, R.R., Caron, M.G. Neuromolecular Med. (2004)