Gene Review:
Cyp2d3 - cytochrome P450, family 2, subfamily d,...
Rattus norvegicus
Synonyms:
CYPIID3, Cyp2d-3, Cyp2d13, Cyp2d6, Cytochrome P450 2D3, ...
- Characterization of a human liver cytochrome P-450 involved in the oxidation of debrisoquine and other drugs by using antibodies raised to the analogous rat enzyme. Distlerath, L.M., Guengerich, F.P. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Purification and characterization of the rat liver microsomal cytochrome P-450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism. Larrey, D., Distlerath, L.M., Dannan, G.A., Wilkinson, G.R., Guengerich, F.P. Biochemistry (1984)
- Does the [3H]mepyramine binding site represent the histamine H1 receptor? Re-examination of the histamine H1 receptor with quinine. Liu, Q., Horio, Y., Fujimoto, K., Fukui, H. J. Pharmacol. Exp. Ther. (1994)
- Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein. Masubuchi, Y., Araki, J., Narimatsu, S., Suzuki, T. Biochem. Pharmacol. (1992)
- Sex and strain differences in hepatic debrisoquine 4-hydroxylase activity of the rat. Kahn, G.C., Rubenfield, M., Davies, D.S., Murray, S., Boobis, A.R. Drug Metab. Dispos. (1985)
- Purification and characterization of [3H]mepyramine (histamine H1 antagonist)-binding protein from rat liver: a highly homologous protein with cytochrome P450 2D. Fukui, H., Mizuguchi, H., Liu, Y.Q., Wang, N.P., Hayashi, H., Kangawa, K., Wakamiya, T., Leurs, R., Shiba, T., Matsuo, H. J. Biochem. (1995)
- Impairment of debrisoquine 4-hydroxylase and related monooxygenase activities in the rat following treatment with propranolol. Masubuchi, Y., Fujita, S., Chiba, M., Kagimoto, N., Umeda, S., Suzuki, T. Biochem. Pharmacol. (1991)
- Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats. Suzuki, T., Narimatsu, S., Fujita, S., Masubuchi, Y., Umeda, S., Imaoka, S., Funae, Y. Drug Metab. Dispos. (1992)
- Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices. Hashemi, E., Till, C., Ioannides, C. Toxicology (2000)
- Inhibition and induction of cytochrome P450 isozymes after repetitive administration of imipramine in rats. Masubuchi, Y., Takahashii, C., Fujio, N., Horie, T., Suzuki, T., Imaoka, S., Funae, Y., Narimatsu, S. Drug Metab. Dispos. (1995)