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Gene Review

rpb2  -  RNA polymerase II complex subunit Rpb2

Schizosaccharomyces pombe 972h-

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High impact information on rpb2

  • To understand the differential roles of two pathways, we examined strand-specific damage removal at the myo2 and rpb2 loci [1].
  • The protein-to-mRNA ratio or the translation efficiency is low for the rpb1, rpb2, rpb3 and rpb11 genes, encoding the homologues of subunits beta', beta, alpha and alpha, respectively, of the prokaryotic RNA polymerase core enzyme [2].
  • When these mutant rpb2 alleles were expressed in an rpb2-disrupted S. pombe strain, all the mutants grew as well as the wild-type parent and did not show any clear defective phenotypes [3].


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