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Gene Review

pad-2  -  Protein PAD-2

Caenorhabditis elegans

 
 
 
 
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High impact information on pad-2

  • To gain insight into the biological role of C21orf80 and its potential role in DS, we isolated its C. elegans ortholog, pad-2, and performed RNA interference (RNAi) and overexpression experiments. pad-2(RNAi) embryos showed failure to undergo normal morphogenesis [1].

References

  1. The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development. Menzel, O., Vellai, T., Takacs-Vellai, K., Reymond, A., Mueller, F., Antonarakis, S.E., Guipponi, M. Genomics (2004) [Pubmed]
 
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