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Gene Review:

26S mRNA - structural polyprotein precursor

Venezuelan equine encephalitis virus

Sneider, J.M. et al., Johnson, B.J. et al.

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Disease relevance of 26S mRNA

The nucleotide and deduced amino acid sequences of the structural proteins of the TC-83 vaccine strain of Venezuelan equine encephalitis (VEE) virus have been determined from a cDNA clone containing the 26S mRNA coding region [1].

High impact information on 26S mRNA

To investigate the likelihood that this epizootic VEE virus, identified as VEE antigenic subtype I-AB, evolved from enzootic viruses extant in the region, we cloned and sequenced the 26S mRNA region of the genomes of the Florida VEE subtype II virus, strain Everglades Fe3-7c, and the Middle American subtype I-E virus, strain Mena II [2].

References

Molecular determinants of alphavirus neurovirulence: nucleotide and deduced protein sequence changes during attenuation of Venezuelan equine encephalitis virus. Johnson, B.J., Kinney, R.M., Kost, C.L., Trent, D.W. J. Gen. Virol. (1986) [Pubmed]
Molecular evidence that epizootic Venezuelan equine encephalitis (VEE) I-AB viruses are not evolutionary derivatives of enzootic VEE subtype I-E or II viruses. Sneider, J.M., Kinney, R.M., Tsuchiya, K.R., Trent, D.W. J. Gen. Virol. (1993) [Pubmed]

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