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Gene Review:

invertase - invertase

Klebsiella pneumoniae CG43

Aulkemeyer, P. et al., Titgemeyer, F. et al., Sprenger, G.A. et al.

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Disease relevance of invertase

Sucrose-positive derivatives of Escherichia coli K-12, containing the plasmid pUR400, and of Klebsiella pneumoniae hydrolyse intracellular sucrose 6-phosphate by means of an invertase into D-glucose 6-phosphate and free D-fructose [1].

High impact information on invertase

Gene scrA codes for an Enzyme IIScr (IIScr) transport protein of the phosphoenolpyruvate-dependent carbohydrate: phosphotransferase system (PTS), while scrB encodes a sucrose 6-phosphate specific invertase [2].
This sugar phosphate is hydrolysed by a hydrolase (invertase, gene scrB) to generate glucose 6-phosphate and free fructose [3].

References

Molecular analysis of two fructokinases involved in sucrose metabolism of enteric bacteria. Aulkemeyer, P., Ebner, R., Heilenmann, G., Jahreis, K., Schmid, K., Wrieden, S., Lengeler, J.W. Mol. Microbiol. (1991) [Pubmed]
Molecular analysis of the scrA and scrB genes from Klebsiella pneumoniae and plasmid pUR400, which encode the sucrose transport protein Enzyme II Scr of the phosphotransferase system and a sucrose-6-phosphate invertase. Titgemeyer, F., Jahreis, K., Ebner, R., Lengeler, J.W. Mol. Gen. Genet. (1996) [Pubmed]
Analysis of sucrose catabolism in Klebsiella pneumoniae and in Scr+ derivatives of Escherichia coli K12. Sprenger, G.A., Lengeler, J.W. J. Gen. Microbiol. (1988) [Pubmed]

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