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Gene Review

UL6  -  dodecamer located at one capsid vertex in...

Human herpesvirus 1

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Disease relevance of UL6

  • Studies to localize the herpes simplex virus 1 portal protein encoded by U(L)6, the putative terminase components encoded by U(L)15, U(L) 28, and U(L)33, the minor capsid proteins encoded by U(L)17, and the major scaffold protein ICP35 were conducted [1].
  • Formation of portal-containing capsids minimally requires the four structural proteins (VP5, VP19C, VP23, and UL6) and a scaffolding protein (UL26.5) [2].

High impact information on UL6


Analytical, diagnostic and therapeutic context of UL6

  • By electron microscopy and image analysis, we find that baculovirus-expressed UL6 is polymorphic, consisting of rings of 11-, 12-, 13-, and 14-fold symmetry [5].


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