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Gene Review

AP2B1  -  adaptor-related protein complex 2, beta 1...

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High impact information on AP2B1


Biological context of AP2B1


Other interactions of AP2B1

  • Antibodies raised against the 70-kDa group of heat-shock proteins (Hsp70) recognize a 70-kDa polypeptide in the beta-adaptin-containing fractions [5].

Analytical, diagnostic and therapeutic context of AP2B1

  • After dissociation with 0.5 M Tris/HCl the CCV coat polypeptides were subjected to gel filtration in order to separate clathrin triskelions from beta-adaptin-containing fractions [5].


  1. Adaptor self-aggregation, adaptor-receptor recognition and binding of alpha-adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits. Chang, M.P., Mallet, W.G., Mostov, K.E., Brodsky, F.M. EMBO J. (1993) [Pubmed]
  2. Conservation and diversity in families of coated vesicle adaptins. Ponnambalam, S., Robinson, M.S., Jackson, A.P., Peiperl, L., Parham, P. J. Biol. Chem. (1990) [Pubmed]
  3. Identification of a beta-type adaptin in plant clathrin-coated vesicles. Holstein, S.E., Drucker, M., Robinson, D.G. J. Cell. Sci. (1994) [Pubmed]
  4. Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis. Milano, S.K., Pace, H.C., Kim, Y.M., Brenner, C., Benovic, J.L. Biochemistry (2002) [Pubmed]
  5. Localization and properties of kinases in clathrin-coated vesicles from zucchini hypocotyls. Drucker, M., Happel, N., Robinson, D.G. Eur. J. Biochem. (1996) [Pubmed]
  6. Interaction of Shc with adaptor protein adaptins. Okabayashi, Y., Sugimoto, Y., Totty, N.F., Hsuan, J., Kido, Y., Sakaguchi, K., Gout, I., Waterfield, M.D., Kasuga, M. J. Biol. Chem. (1996) [Pubmed]
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