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PECAM1  -  platelet/endothelial cell adhesion molecule 1

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Analytical, diagnostic and therapeutic context of PECAM1


  1. Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule? Osawa, M., Masuda, M., Kusano, K., Fujiwara, K. J. Cell Biol. (2002) [Pubmed]
  2. Lactosylceramide recruits PKCalpha/epsilon and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells. Gong, N., Wei, H., Chowdhury, S.H., Chatterjee, S. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  3. Vascular endothelial platelet endothelial adhesion molecule-1 (PECAM-1) expression is decreased by TNF-alpha and IFN-gamma. Evidence for cytokine-induced destabilization of messenger ribonucleic acid transcripts in bovine endothelial cells. Stewart, R.J., Kashour, T.S., Marsden, P.A. J. Immunol. (1996) [Pubmed]
  4. Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2. Tai, L.K., Zheng, Q., Pan, S., Jin, Z.G., Berk, B.C. J. Biol. Chem. (2005) [Pubmed]
  5. Platelet endothelial cell adhesion molecule, PECAM-1, modulates cell migration. Schimmenti, L.A., Yan, H.C., Madri, J.A., Albelda, S.M. J. Cell. Physiol. (1992) [Pubmed]
  6. Freshly isolated bovine coronary endothelial cells do not express the BK Ca channel gene. Gauthier, K.M., Liu, C., Popovic, A., Albarwani, S., Rusch, N.J. J. Physiol. (Lond.) (2002) [Pubmed]
  7. Platelet endothelial cell adhesion molecule-1 expression modulates endothelial cell migration in vitro. Kim, C.S., Wang, T., Madri, J.A. Lab. Invest. (1998) [Pubmed]
  8. The angiogenesis inhibitor AGM-1470 selectively increases E-selectin. Budson, A.E., Ko, L., Brasel, C., Bischoff, J. Biochem. Biophys. Res. Commun. (1996) [Pubmed]
  9. Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 induced by lysophosphatidylcholine in cultured endothelial cells. Ochi, H., Kume, N., Nishi, E., Moriwaki, H., Masuda, M., Fujiwara, K., Kita, T. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  10. Expression of platelet-endothelial cell adhesion molecule-1 in human umbilical vein endothelial cells by exposure to advanced glycosylation end products and inflammatory mediators. Meng, D., Liu, N. Chin. Med. J. (2003) [Pubmed]
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