Gene Review:
NEK8 - NIMA-related kinase 8
Homo sapiens
Synonyms:
JCK, NEK12A, NPHP9, Never in mitosis A-related kinase 8, NimA-related protein kinase 8, ...
- Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors. Bowers, A.J., Boylan, J.F. Gene (2004)
- Melanosomal antigenic expression on the cell surface and intracellular subunits within melanogenic compartments of pigment cells: analysis by antimelanosome-associated monoclonal antibody. Hayashibe, K., Mishima, Y., Ichihashi, M., Kawai, M. J. Invest. Dermatol. (1986)
- New cell lines of human breast cancer origin. Calaf, G., Abarca-Quinones, J., Feuilhade, F., Beaune, J., Dupre, G., Orrico, M., Barnabas-Sohi, N., Kouyoumdjian, J.C. Breast Cancer Res. Treat. (1992)
- Chemosensitivity of human pancreatic cancer cell lines serially transplanted in nude mouse. Tomikawa, M., Kubota, T., Takahashi, S., Matsuzaki, S.W., Kitajima, M. Anticancer Res. (1998)
- Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2. Holland, P.M., Milne, A., Garka, K., Johnson, R.S., Willis, C., Sims, J.E., Rauch, C.T., Bird, T.A., Virca, G.D. J. Biol. Chem. (2002)
- Establishment and characterization of chromosomal aberrations in human cholangiocarcinoma cell lines by cross-species color banding. Kim, D.G., Park, S.Y., You, K.R., Lee, G.B., Kim, H., Moon, W.S., Chun, Y.H., Park, S.H. Genes Chromosomes Cancer (2001)
- Nek8 mutation causes overexpression of galectin-1, sorcin, and vimentin and accumulation of the major urinary protein in renal cysts of jck mice. Valkova, N., Yunis, R., Mak, S.K., Kang, K., Kültz, D. Mol. Cell Proteomics (2005)
- Increased renal calcium reabsorption by parathyroid hormone-related protein is a causative factor in the development of humoral hypercalcemia of malignancy refractory to osteoclastic bone resorption inhibitors. Onuma, E., Azuma, Y., Saito, H., Tsunenari, T., Watanabe, T., Hirabayashi, M., Sato, K., Yamada-Okabe, H., Ogata, E. Clin. Cancer Res. (2005)