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Gene Review:

Gdi2 - GDP dissociation inhibitor 2

Rattus norvegicus

Synonyms: GDI-2, GDI-3, Gdi3, Guanosine diphosphate dissociation inhibitor 2, Rab GDI beta, ...

Nishimura, N. et al., Araki, K. et al.

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High impact information on Gdi2

Reverse transcription-polymerase chain reaction analysis revealed that astrocytes expressed rat rab GDI beta gene but not rat rab GDI alpha gene [1].
The partial amino acid sequence analysis revealed that it was identical with rat Rab GDI beta [2].

Analytical, diagnostic and therapeutic context of Gdi2

Northern blot analysis revealed that rab GDI alpha mRNA was expressed abundantly in brain but much less in other tissues, whereas rat rab GDI beta mRNA was ubiquitously expressed [1].

References

Molecular cloning and characterization of two rab GDI species from rat brain: brain-specific and ubiquitous types. Nishimura, N., Nakamura, H., Takai, Y., Sano, K. J. Biol. Chem. (1994) [Pubmed]
Purification and characterization of Rab GDI beta from rat brain. Araki, K., Nakanishi, H., Hirano, H., Kato, M., Sasaki, T., Takai, Y. Biochem. Biophys. Res. Commun. (1995) [Pubmed]

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