Gene Review:
Bok - BCL2-related ovarian killer
Rattus norvegicus
Synonyms:
Bcl-2-related ovarian killer protein
- Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. Hsu, S.Y., Kaipia, A., McGee, E., Lomeli, M., Hsueh, A.J. Proc. Natl. Acad. Sci. U.S.A. (1997)
- A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro. Hsu, S.Y., Hsueh, A.J. J. Biol. Chem. (1998)
- The expression and regulation of Bcl-2-related ovarian killer (Bok) mRNA in the developing and adult rat testis. Suominen, J.S., Yan, W., Toppari, J., Kaipia, A. Eur. J. Endocrinol. (2001)
- Induction of apoptosis in the lung but not in the liver of rats receiving intra-tracheal instillations of chromium(VI). D'Agostini, F., Izzotti, A., Bennicelli, C., Camoirano, A., Tampa, E., De Flora, S. Carcinogenesis (2002)
- Differential expression of stress response genes in the H-Tx rat model of congenital hydrocephalus. Morgan, F.W., Stewart, J.A., Smith, A.N., Tarnuzzer, R.W. Brain Res. Mol. Brain Res. (2005)