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Gene Review: 

foxb1.1  -  forkhead box B1.1

Danio rerio

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High impact information on foxb1.1

  • At mid-gastrula, expression of these genes defines a very early pattern in the presumptive neurectoderm, with opl later expressed in the telencephalon, and fkh5 in the diencephalon and more posterior neurectoderm [1].
  • In order to study these events, we isolated zebrafish homologs of two neural markers, odd-paired-like (opl), which encodes a zinc finger protein, and fkh5, which encodes a forkhead domain protein [1].
  • Transcripts of fkd3 and fkd5 (class II) are mainly detected in the cells of the ectoderm which form neural tissues, as is the case for genes of this class in other species [2].

References

  1. Determination of the zebrafish forebrain: induction and patterning. Grinblat, Y., Gamse, J., Patel, M., Sive, H. Development (1998) [Pubmed]
  2. fork head domain genes in zebrafish. Odenthal, J., Nüsslein-Volhard, C. Dev. Genes Evol. (1998) [Pubmed]
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