High impact information on hsp90ab1

• Furthermore, development of the notochord, which provides many of the signals required for proper somite patterning and which does not express detectable levels of either hsp90alpha or hsp90beta mRNA, was similarly unaffected in geldanamycin-treated embryos [1].

Biological context of hsp90ab1

• In expression studies using Northern blot analysis, hsp 90 beta mRNA was found to be present at control temperatures throughout normal embryonic development whereas hsp 90 alpha mRNA was barely detectable [2].

Regulatory relationships of hsp90ab1

• Thus, the hsp 90 alpha gene is strongly upregulated during heat shock in zebrafish embryos whereas expression of the hsp 90 beta gene appears to be weakly induced [2].

Other interactions of hsp90ab1

• HSP 90 alpha and HSP 90 beta genes are present in the zebrafish and are differentially regulated in developing embryos [2].

References