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Gene Review:

dotB - defect in organelle trafficking protein...

Legionella pneumophila str. Paris

This record was discontinued.

Bandyopadhyay, P. et al.

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High impact information on dotB

Following encystment in Acanthamoeba castellanii and reversion of cysts to amoeba trophozoites, dotA and dotB mutants exhibited intracellular multiplication in amoebae [1].

Anatomical context of dotB

Following incubation of stationary-phase cultures in water, mutants in dotA and dotB, essential for function of the type IVB secretion system, exhibited entry and delay of phagosome acidification comparable to that of strain JR32 [1].

References

Environmental mimics and the Lvh type IVA secretion system contribute to virulence-related phenotypes of Legionella pneumophila. Bandyopadhyay, P., Liu, S., Gabbai, C.B., Venitelli, Z., Steinman, H.M. Infect. Immun. (2007) [Pubmed]

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