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Gene Review

ompb  -  olfactory marker protein b

Danio rerio

Synonyms: SO:0000704, omp, zgc:101697
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High impact information on omp

  • Selective targeting of zebrafish olfactory receptor neurons by the endogenous OMP promoter [1].
  • Here, we found that these OSNs express different sets of signal transduction machineries: the ciliated OSNs express OR-type odorant receptors, cyclic nucleotide-gated channel A2 subunit, and olfactory marker protein (OMP), whereas the microvillous OSNs express V2R-type receptors and transient receptor potential channel C2 (TRPC2) [2].
  • To visualize patterns of axonal projection from the two types of OSNs to the olfactory bulb (OB), we generated transgenic zebrafish in which spectrally distinct fluorescent proteins are expressed in the ciliated and microvillous OSNs under the control of OMP and TRPC2 gene promoters, respectively [2].
  • By injection of vectors with EGFP under control of either the OMP or the nAChRbeta3 gene promoter, we followed the development of individual olfactory sensory neurons and RGCs [3].


  1. Selective targeting of zebrafish olfactory receptor neurons by the endogenous OMP promoter. Celik, A., Fuss, S.H., Korsching, S.I. Eur. J. Neurosci. (2002) [Pubmed]
  2. Mutually exclusive glomerular innervation by two distinct types of olfactory sensory neurons revealed in transgenic zebrafish. Sato, Y., Miyasaka, N., Yoshihara, Y. J. Neurosci. (2005) [Pubmed]
  3. Neuron-specific gene manipulations to transparent zebrafish embryos. Yoshida, T., Mishina, M. Methods in cell science : an official journal of the Society for In Vitro Biology. (2003) [Pubmed]
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