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Gene Review

kif20a  -  kinesin family member 20A

Danio rerio

Synonyms: SO:0000704
 
 
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High impact information on mt2

  • In brain, only mt1, mt2 and c-jun genes were up-regulated after 21 days [1].
  • Cadmium concentrations were determined in the four organs and metallothionein (MT) protein levels investigated in brain, liver and gills [1].
  • The zebrafish embryo-larvae were used for the in vivo study, and MT gene expression was studied during the development from fertilization (8hpf) to embryo-larval stage using real-time PCR [2].
  • Comparison with the large-scale expressed sequence tags sequencing approach revealed highly expressed transcripts that were not previously known to be expressed at high levels in fish ovaries, like the short-sized polarized metallothionein 2 transcript [3].
  • To verify the use of zebrafish MT gene promoter for aquatic toxicology studies, an 835 bp zebrafish MT (zMT) gene promoter with four putative metal regulatory elements (MREs) was isolated by DNA walking method and characterized for metal induction of gene transcription using transient expression assays in a zebrafish caudal fin cell line, SJD [4].

References

 
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