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Gene Review:

blaTEM1 - beta-lactamase TEM1

Salmonella typhimurium

Kehrenberg, C. et al., Peirano, G. et al., Hradecka, H. et al.

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High impact information on blaTEM1

Sulphonamide resistance was primarily mediated by sul2 and sul3, tetracycline resistance by tet(B) and tet(A), chloramphenicol resistance by catA1, streptomycin resistance by strA and ampicillin resistance by blaTEM. blaCTX and blaCMY-2 were found in cephalosporin-resistant isolates [1].
It carried a conjugative plasmid, pINF5, on which a qnrS gene was detected in close proximity to a Tn3-like, blaTEM-1-carrying transposon [2].
Ampicillin resistance was confirmed to be encoded by the blaTEM gene located on the TnA transposon [3].

References

Occurrence of integrons and antimicrobial resistance genes among Salmonella enterica from Brazil. Peirano, G., Agersø, Y., Aarestrup, F.M., dos Reis, E.M., dos Prazeres Rodrigues, D. J. Antimicrob. Chemother. (2006) [Pubmed]
Identification of the plasmid-borne quinolone resistance gene qnrS in Salmonella enterica serovar Infantis. Kehrenberg, C., Friederichs, S., de Jong, A., Michael, G.B., Schwarz, S. J. Antimicrob. Chemother. (2006) [Pubmed]
An outbreak of human salmonellosis caused by ampicillin-resistant Salmonella enterica serovar Enteritidis PT13 in the Czech Republic. Hradecka, H., Kolackova, I., Karpiskova, R., Rychlik, I. Epidemiol. Infect. (2006) [Pubmed]

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