Gene Review:
aroA - 5-enolpyruvylshikimate-3-phosphate...
Haemophilus influenzae 86-028NP
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Disease relevance of aroA
- Cloning and sequencing of the Haemophilus influenzae aroA gene [1].
- The PCR-produced probe from H. influenzae DNA was used to identify a recombinant lambda phage from which the rest of H. influenzae aroA was subcloned and sequenced [1].
High impact information on aroA
- The stop codon of the putative H. influenzae purN gene overlaps the start codon for H. influenzae aroA, suggesting that the two genes may form an operon and that they may be translationally coupled [1].
- This study was designed to clone the aroA gene (encoding 5-enolpyruvylshikimate-3-phosphate synthase [EPSPS]) from Haemophilus influenzae using a mixed-primer polymerase chain reaction (PCR) [1].
Associations of aroA with chemical compounds
- The upstream sequence of aroA, when translated, results in a protein with strong homology to the purN gene product, glycinamide ribonucleotide transformylase [1].
References
- Cloning and sequencing of the Haemophilus influenzae aroA gene. Maskell, D. Gene (1993) [Pubmed]
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