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Gene Review

Cyt-b5-r  -  Cytochrome b5-related

Drosophila melanogaster

Synonyms: CG13279, Cyt-b, Cyt-b5, Cytb, Cytb5, ...
 
 
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High impact information on Cyt-b5-r

  • We report the characterization of a transcription unit at the second chromosome locus 36B, designated TU-36B which is adjacent to the 3' end of the Drosophila myosin heavy-chain (Mhc) gene [1].
  • The Drosophila Cyt-b proteins show sequence similarity to other b-type cytochromes, especially in the N-terminal heme-binding domain, and may be targeted to the mitochondrial membrane [2].
  • We report the characterization of the cytochrome b5 (Cyt-b) gene of Drosophila virilis and compare its structure to the Cyt-b gene of Drosophila melanogaster [2].
  • These results add to other recent observations of pseudogenes suggesting the frequent transfer of mitochondrial DNA (mtDNA) genes to the nucleus and reinforces the necessity of great care in interpreting PCR-generated Cyt b sequences used in population or evolutionary studies in freshwater crayfish and crustaceans more generally [3].
  • We amplified and sequenced fragments of the mitochondrial Cyt b gene from 14 individuals of C. destructor using polymerase chain reaction (PCR) with primers designed from conserved regions of Penaeus monodon and Drosophila melanogaster mitochondrial genomes [3].
 

Biological context of Cyt-b5-r

 

Associations of Cyt-b5-r with chemical compounds

  • This is contrary to an earlier report that the A. salina ND1 and Cyt b genes are immediately adjacent to each other [5].
 

Analytical, diagnostic and therapeutic context of Cyt-b5-r

  • Comparison of in situ hybridization of Mhc specific and TU-36B specific probes to tissue sections demonstrates that both mRNAs are predominantly transcribed in the same muscle tissues of the developing fly [1].

References

 
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