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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Btrc  -  beta-transducin repeat containing E3...

Rattus norvegicus

 
 
 
 
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High impact information on Btrc

  • These findings suggest that beta-TrCP1 increases the rate of NF-kappaB activation but is not rate-limiting in response to TNF in VSMCs [1].
  • In contrast, VSMCs harboring a dominant-negative beta-TrCP1 transgene lacking the F-box domain exhibited a reduction in serum-stimulated NF-kB activity but no alteration in response to tumor necrosis factor (TNF) [1].

References

  1. The role of [beta]-transducin repeat-containing protein ([beta]-TrCP) in the regulation of NF-[kappa]B in vascular smooth muscle cells. Wang, X., Adhikari, N., Li, Q., Guan, Z., Hall, J.L. Arterioscler. Thromb. Vasc. Biol. (2004) [Pubmed]
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