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Gene Review

GLDC  -  glycine dehydrogenase (decarboxylating)

Gallus gallus

 
 
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Disease relevance of GLDC

  • Cloning of the glycine decarboxylase cDNA will permit a direct test of whether it functions as a cell surface co-receptor or as a co-factor in the DHBV replication cycles [1].
 

High impact information on GLDC

 

Biological context of GLDC

 

Associations of GLDC with chemical compounds

  • The mitochondrial glycine cleavage system. Functional association of glycine decarboxylase and aminomethyl carrier protein [6].
  • Comparison of this deduced amino acid sequence with the sequence of a pyridoxal phosphate-containing peptide isolated from the P subunit of chicken liver glycine decarboxylase shows remarkable conservation [2].
  • The exchange of glycine carboxyl carbon with CO2 catalyzed by the combination of chicken liver glycine decarboxylase (P-protein) and aminomethyl carrier protein (H-protein) was markedly inhibited by various divalent cations, although extents of inhibition by individual metal ions varied considerably [7].

References

 
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