Gene Review:
DCX - doublecortin
Gallus gallus
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High impact information on DCX
- In postmigratory Purkinje cells, DCX and DCLK both colocalized to the cell membrane, although DCLK was also distributed more generally throughout the cell soma [1].
- DCX is known to belong to a novel protein family defined by sequence homology and the presence of a conserved microtubule-binding domain, but the functions of other members of this family are still undefined [1].
- DCX and DCLK are widely expressed in pallial and subpallial structures, including the telencephalon, optic tectum, and cerebellum, in similar distribution patterns [1].
References
- Expression of doublecortin (DCX) and doublecortin-like kinase (DCLK) within the developing chick brain. Capes-Davis, A., Tolhurst, O., Dunn, J.M., Jeffrey, P.L. Dev. Dyn. (2005) [Pubmed]
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