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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

rsbW  -  serine-protein kinase RsbW

Staphylococcus aureus RF122

 
 
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Disease relevance of rsbW

 

High impact information on rsbW

  • Increased sigma(B) activity was associated with point mutations in rsbW, releasing sigma(B) from sequestration by the anti-sigma factor RsbW, or to promoter mutations increasing the sigma(B)/RsbW ratio [2].
  • The rsbW (orf159) gene is immediately upstream of sigB [1].

References

  1. The Staphylococcus aureus rsbW (orf159) gene encodes an anti-sigma factor of SigB. Miyazaki, E., Chen, J.M., Ko, C., Bishai, W.R. J. Bacteriol. (1999) [Pubmed]
  2. Teicoplanin stress-selected mutations increasing sigma(B) activity in Staphylococcus aureus. Bischoff, M., Berger-Bächi, B. Antimicrob. Agents Chemother. (2001) [Pubmed]
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