Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

ago - archipelago

Drosophila melanogaster

Synonyms: Ago, CG15010, DmFbw7, Dmel\CG15010, F-box and WD-40 domain-containing protein 7, ...

Pinto, F.M. et al., Shcherbata, H.R. et al., Moberg, K.H. et al., Schwab, M. et al.

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High impact information on ago

The Archipelago protein binds directly to Cyclin E and probably targets it for ubiquitin-mediated degradation [1].
Cell cycle. Archipelago of destruction [2].
We also show that Archipelago (Ago), a SCF-regulator is dispensable for mitosis, but crucial for endocycle progression in follicle epithelium [3].
In addition, sex-linked allozymes and mtDNA data show a large divergence between the geologically younger western islands of the Canarian Archipelago and the older central ones, finding strong founder effects in the former [4].

References

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines. Moberg, K.H., Bell, D.W., Wahrer, D.C., Haber, D.A., Hariharan, I.K. Nature (2001) [Pubmed]
Cell cycle. Archipelago of destruction. Schwab, M., Tyers, M. Nature (2001) [Pubmed]
The mitotic-to-endocycle switch in Drosophila follicle cells is executed by Notch-dependent regulation of G1/S, G2/M and M/G1 cell-cycle transitions. Shcherbata, H.R., Althauser, C., Findley, S.D., Ruohola-Baker, H. Development (2004) [Pubmed]
Population genetic structure and colonization sequence of Drosophila subobscura in the Canaries and Madeira Atlantic Islands as inferred by autosomal, sex-linked and mtDNA traits. Pinto, F.M., Brehm, A., Hernández, M., Larruga, J.M., González, A.M., Cabrera, V.M. J. Hered. (1997) [Pubmed]

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sel-10	Caenorhabditis elegans
LOC419074	Gallus gallus
MGG_06372	Magnaporthe oryzae 70-15
NCU06483	Neurospora crassa OR74A

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