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Gene Review

MDM2  -  MDM2 oncogene, E3 ubiquitin protein ligase

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High impact information on MDM2

  • Other p53-related genes including p21WAF1, p27Kip1, MDM-2, and the p16INK4a alternate reading frame (ARF) sequence showed similar patterns of differential mRNA expression [1].

References

  1. Modulation of p53 expression and its role in the conversion to a fully immortalized chicken embryo fibroblast line. Christman, S.A., Kong, B.W., Landry, M.M., Kim, H., Foster, D.N. FEBS Lett. (2005) [Pubmed]
 
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