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Gene Review

EFNB1  -  ephrin-B1

Gallus gallus

 
 
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High impact information on EFNB1

  • Spatiotemporal expression patterns of six members of the Eph gene family (EphA4, EphA3, EphB2, ephrin-B1, ephrin-A2, and ephrin-A5) were characterized immunocytochemically at various stages of chick cerebellar development [1].
  • We also provide evidence that the only candidate molecule(s) that induces the growth cone collapse of both sensory and motor axons binds to PNA and is not Sema3A or Ephrin-B [2].
  • EphB2, EphB5, and ephrin-B1 are expressed in dorsal and ventral NL neuropil and at the midline of the brainstem at E10-E12 [3].
  • We report here on the developmental changes in the expression of two other Eph receptors, EphB2 and EphB5, and two ligands, ephrin-B1 and ephrin-B2, in the chick auditory brainstem [3].

References

  1. Eph receptors and ephrins in the developing chick cerebellum: relationship to sagittal patterning and granule cell migration. Karam, S.D., Burrows, R.C., Logan, C., Koblar, S., Pasquale, E.B., Bothwell, M. J. Neurosci. (2000) [Pubmed]
  2. Spinal nerve segmentation in the chick embryo: analysis of distinct axon-repulsive systems. Vermeren, M.M., Cook, G.M., Johnson, A.R., Keynes, R.J., Tannahill, D. Dev. Biol. (2000) [Pubmed]
  3. Expression of EphB receptors and EphrinB ligands in the developing chick auditory brainstem. Cramer, K.S., Karam, S.D., Bothwell, M., Cerretti, D.P., Pasquale, E.B., Rubel, E.W. J. Comp. Neurol. (2002) [Pubmed]
 
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