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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ACTR2  -  ARP2 actin-related protein 2 homolog (yeast)

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High impact information on ACTR2

  • Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts [1].
  • The localization of the Arp2/3 complex mRNAs is dependent on both actin filaments and microtubules, because disruption of either cytoskeletal system (with cytochalasin D and colchicine, respectively) inhibited the localization of all seven subunit mRNAs [1].
  • Arp2/3 complex bound to an F-actin affinity column from gizzard extract [2].
  • Immunoblot analysis of various tissues revealed that the amounts of Arp2/3 subunits were lower in striated muscle than in non-muscle and smooth muscle tissues [2].

References

  1. Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. Mingle, L.A., Okuhama, N.N., Shi, J., Singer, R.H., Condeelis, J., Liu, G. J. Cell. Sci. (2005) [Pubmed]
  2. Characterization of Arp2/3 complex in chicken tissues. Terasaki, A.G., Morikawa, K., Suzuki, H., Oshima, K., Ohashi, K. Cell Struct. Funct. (2002) [Pubmed]
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