Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

XFO 9-3 - zinc finger protein

Xenopus laevis

Klocke, B. et al., Lu, D. et al., Krepkiy, D. et al., Nagai, K. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of XFO 9-3

Zinc-finger motifs expressed in E. coli and folded in vitro direct specific binding to DNA [1].

High impact information on XFO 9-3

Zinc finger 3 of transcription factor IIIA (Zn-F3) of Xenopus laevis was investigated as a potential redox active site of reaction of Cr (VI) and thiol compounds [2].
Zinc-finger proteins of the classical Cys2His2 type are the most frequently used class of transcription factor and account for about 3% of genes in the human genome [3].
Northern blot analyses of three different members of the FAR subfamily (XFO 6, XFO 9-3 and XFG 68) revealed that each of these genes is transcribed during oogenesis, embryogenesis and in all investigated tissues of adult animals thereby indicating a ubiquitous distribution of transcripts [4].

References

Zinc-finger motifs expressed in E. coli and folded in vitro direct specific binding to DNA. Nagai, K., Nakaseko, Y., Nasmyth, K., Rhodes, D. Nature (1988) [Pubmed]
Model reactions of Cr (VI) with DNA mediated by thiol species. Krepkiy, D., Antholine, W.E., Myers, C., Petering, D.H. Mol. Cell. Biochem. (2001) [Pubmed]
Crystal structure of a zinc-finger-RNA complex reveals two modes of molecular recognition. Lu, D., Searles, M.A., Klug, A. Nature (2003) [Pubmed]
The FAR domain defines a new Xenopus laevis zinc finger protein subfamily with specific RNA homopolymer binding activity. Klocke, B., Köster, M., Hille, S., Bouwmeester, T., Böhm, S., Pieler, T., Knöchel, W. Biochim. Biophys. Acta (1994) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.