The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

XFO 9-3  -  zinc finger protein

Xenopus laevis

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of XFO 9-3

  • Zinc-finger motifs expressed in E. coli and folded in vitro direct specific binding to DNA [1].

High impact information on XFO 9-3

  • Zinc finger 3 of transcription factor IIIA (Zn-F3) of Xenopus laevis was investigated as a potential redox active site of reaction of Cr (VI) and thiol compounds [2].
  • Zinc-finger proteins of the classical Cys2His2 type are the most frequently used class of transcription factor and account for about 3% of genes in the human genome [3].
  • Northern blot analyses of three different members of the FAR subfamily (XFO 6, XFO 9-3 and XFG 68) revealed that each of these genes is transcribed during oogenesis, embryogenesis and in all investigated tissues of adult animals thereby indicating a ubiquitous distribution of transcripts [4].


  1. Zinc-finger motifs expressed in E. coli and folded in vitro direct specific binding to DNA. Nagai, K., Nakaseko, Y., Nasmyth, K., Rhodes, D. Nature (1988) [Pubmed]
  2. Model reactions of Cr (VI) with DNA mediated by thiol species. Krepkiy, D., Antholine, W.E., Myers, C., Petering, D.H. Mol. Cell. Biochem. (2001) [Pubmed]
  3. Crystal structure of a zinc-finger-RNA complex reveals two modes of molecular recognition. Lu, D., Searles, M.A., Klug, A. Nature (2003) [Pubmed]
  4. The FAR domain defines a new Xenopus laevis zinc finger protein subfamily with specific RNA homopolymer binding activity. Klocke, B., Köster, M., Hille, S., Bouwmeester, T., Böhm, S., Pieler, T., Knöchel, W. Biochim. Biophys. Acta (1994) [Pubmed]
WikiGenes - Universities