Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

sumo1-a - small ubiquitin-like modifier 1

Xenopus laevis

Synonyms: Ubl1, dap1, gmp1, ofc10, pic1, ...

Yukita, A. et al., Kim, M. et al., Leach, C.A. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on SUMO-1

Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts [1].
Small ubiqutin-related modifier (SUMO), which is responsible for the ubiquitination-like post-translational modification 'sumoylation', regulates a number of biological processes including, in particular, transcription [2].
NZFP contains a highly conserved sequence designated finger associated box (FAX) and SUMO-1 consensus-binding motifs at the N-terminal half and 10 C2H2 type zinc finger motifs at the C-terminal half, respectively [3].

References

Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts. Leach, C.A., Michael, W.M. J. Cell Biol. (2005) [Pubmed]
XSENP1, a novel sumo-specific protease in Xenopus, inhibits normal head formation by down-regulation of Wnt/beta-catenin signalling. Yukita, A., Michiue, T., Fukui, A., Sakurai, K., Yamamoto, H., Ihara, M., Kikuchi, A., Asashima, M. Genes Cells (2004) [Pubmed]
A novel TBP-interacting zinc finger protein represses transcription by inhibiting the recruitment of TFIIA and TFIIB. Kim, M., Park, C.H., Lee, M.S., Carlson, B.A., Hatfield, D.L., Lee, B.J. Biochem. Biophys. Res. Commun. (2003) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share