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Gene Review:

CYP2B22 - cytochrome P450 2B22

Sus scrofa

Kawahigashi, H. et al.

Kawahigashi, Hirose, Ozawa, Ido, Kojima, Ohkawa, Ohkawa,

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High impact information on CYP2B22

Analysis of substrate specificity of pig CYP2B22 and CYP2C49 towards herbicides by transgenic rice plants [1].
CYP2B22 rice plants showed tolerance towards 12 herbicides including chlortoluron (100 microM), amiprofos-methyl (2.5 microM), pendimethalin (10 microM), metolachlor (2.5 microM), and esprocarb (20 microM) [1].

Other interactions of CYP2B22

Therefore, CYP2B22 and CYP2C49 rice plants became more tolerant to various herbicides than nontransgenic control plants because of accelerated metabolism of the herbicides by the introduced P450 species [1].

References

Analysis of substrate specificity of pig CYP2B22 and CYP2C49 towards herbicides by transgenic rice plants. Kawahigashi, H., Hirose, S., Ozawa, K., Ido, Y., Kojima, M., Ohkawa, H., Ohkawa, Y. Transgenic Res. (2005) [Pubmed]

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