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DUOX1  -  dual oxidase 1

Canis lupus familiaris

 
 
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High impact information on DUOX1

  • The main constituent enzymes belong to the NADPH oxidase (NOX) family (Duox/ThOX for the thyroid and NOX2 /gp91phox for the leukocytes and macrophages), and in both cell types, H2O2 generation is activated by the intracellular generation of Ca2+ and diacylglycerol signals [1].

References

  1. Regulation of H2O2 generation in thyroid cells does not involve Rac1 activation. Fortemaison, N., Miot, F., Dumont, J.E., Dremier, S. Eur. J. Endocrinol. (2005) [Pubmed]
 
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