Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Pisrt1 - polled intersex syndrome regulated...

Mus musculus

Loffler, K.A. et al.

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High impact information on Pisrt1

Pisrt1, a gene implicated in XX sex reversal, is expressed in gonads of both sexes during mouse development [1].
Expression analyses indicated that Pisrt1 is transcribed, and its mRNA polyadenylated and exported to the cytoplasm, but no significant open reading frames were found in a 1.5kb mouse genomic region corresponding to goat Pisrt1 [1].

Analytical, diagnostic and therapeutic context of Pisrt1

Pisrt1 transcripts were expressed very broadly among tissues of the developing mouse embryo, and at similar levels in male and female gonads at each stage examined, as determined by in situ hybridisation and RT-PCR [1].

References

Pisrt1, a gene implicated in XX sex reversal, is expressed in gonads of both sexes during mouse development. Loffler, K.A., Combes, A.N., Wilhelm, D., Beverdam, A., Bowles, J., Koopman, P. Mol. Genet. Metab. (2005) [Pubmed]

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