Gene Review:
Prat - Phosphoribosylamidotransferase
Drosophila melanogaster
Synonyms:
ATase, Amidophosphoribosyltransferase, CG2867, DmPrat, Dmel\CG2867, ...
- The purine synthesis gene Prat2 is required for Drosophila metamorphosis, as revealed by inverted-repeat-mediated RNA interference. Ji, Y., Clark, D.V. Genetics (2006)
- Identification of trans-dominant modifiers of Prat expression in Drosophila melanogaster. Malmanche, N., Clark, D.V. Genetics (2003)
- The PRAT purine synthesis gene duplication in Drosophila melanogaster and Drosophila virilis is associated with a retrotransposition event and diversification of expression patterns. Malmanche, N., Drapeau, D., Cafferty, P., Ji, Y., Clark, D.V. J. Mol. Evol. (2003)
- Drosophila melanogaster Prat, a purine de novo synthesis gene, has a pleiotropic maternal-effect phenotype. Malmanche, N., Clark, D.V. Genetics (2004)
- Molecular and genetic analyses of Drosophila Prat, which encodes the first enzyme of de novo purine biosynthesis. Clark, D.V. Genetics (1994)
- The Drosophila melanogaster ade5 gene encodes a bifunctional enzyme for two steps in the de novo purine synthesis pathway. O'Donnell, A.F., Tiong, S., Nash, D., Clark, D.V. Genetics (2000)