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Gene Review

CYP3A7  -  cytochrome P450 A 37

Gallus gallus

 
 
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Disease relevance of CYP3A37

  • Squalestatin1 (SQ1), a potent inhibitor of squalene synthase produced a dose-dependent induction of cytochromes P450 CYP2H1 and CYP3A37 mRNAs in chicken hepatoma cells [1].
 

High impact information on CYP3A37

References

  1. A Link between cholesterol levels and phenobarbital induction of cytochromes P450. Ourlin, J.C., Handschin, C., Kaufmann, M., Meyer, U.A. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  2. Cloning and functional expression of a first inducible avian cytochrome P450 of the CYP3A subfamily (CYP3A37). Ourlin, J.C., Baader, M., Fraser, D., Halpert, J.R., Meyer, U.A. Arch. Biochem. Biophys. (2000) [Pubmed]
 
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