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Gene Review

Desat2  -  Desaturase 2

Drosophila melanogaster

Synonyms: 7-11HD, CG5925, Dmel\CG5925, Fad, desat, ...
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High impact information on desat2

  • Taken together with previous molecular genetic evidence, our results suggest that ds2 is one of the genes responsible for adaptive divergence of the Z and M races of D. melanogaster [1].
  • To probe the role of natural selection in species origin, we performed a DNA polymorphism survey of the Drosophila melanogaster desaturase2 (ds2) locus. ds2 is responsible for a cuticular hydrocarbon difference between two behaviorally isolated races--Zimbabwe (Z) and Cosmopolitan (M) [1].
  • Several candidate genes, such as desaturase2 and Odorant receptor 63a, were additionally subjected to quantitative RT-PCR analysis [2].


  1. Adaptive loss of an old duplicated gene during incipient speciation. Greenberg, A.J., Moran, J.R., Fang, S., Wu, C.I. Mol. Biol. Evol. (2006) [Pubmed]
  2. Gene expression polymorphism in Drosophila populations. Michalak, P., Malone, J.H., Lee, I.T., Hoshino, D., Ma, D. Mol. Ecol. (2007) [Pubmed]
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