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Gene Review

BRIP1  -  BRCA1 interacting protein C-terminal...

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Disease relevance of BRIP1

  • These genes encode components of the FA "core" complex, a key factor FancD2, the familial breast cancer suppressor BRCA2/FancD1, and Brip1/FancJ helicase [1].

References

  1. Functional interplay between BRCA2/FancD1 and FancC in DNA repair. Kitao, H., Yamamoto, K., Matsushita, N., Ohzeki, M., Ishiai, M., Takata, M. J. Biol. Chem. (2006) [Pubmed]
 
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