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Gene Review

LCT  -  lactase

Gallus gallus

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High impact information on LCT

  • A reverse transcriptase-PCR strategy using a degenerate mixture of oligonucleotides was developed to search for the presence of transcripts similar in sequence to the mammalian lactase mRNA in the digestive tracts of a bird (the chicken) and an invertebrate (the mussel) [1].
  • They also suggested that the chicken protein and one mussel protein are integral molecules anchored in the cell membrane by a C-terminal transmembrane anchor, like lactase [1].
  • 3. After d 7 postnatally only traces of lactase and trehalase activity were found in the enterocytes [2].
  • 2. The specific activities of maltase, lactase and trehalase were greatest on d 18 of embryonic development [2].
  • Serum concentrations of the albumin, total protein, cholesterol, uric acid, triglycerides, and enzyme activities of alanine transaminase, aspartate aminotransferase, lactase dehydrogenase, and creatine phosphokinase were also evaluated [3].


  1. Identification of homologues of the mammalian intestinal lactase gene in non-mammals (birds and molluscs). Freund, J.N., Jost, B., Lorentz, O., Duluc, I. Biochem. J. (1997) [Pubmed]
  2. Development of disaccharidase activity in the small intestine of broiler chickens. Chotinsky, D., Toncheva, E., Profirov, Y. Br. Poult. Sci. (2001) [Pubmed]
  3. The use of Saccharomyces cerevisiae to suppress the effects of aflatoxicosis in broiler chicks. Stanley, V.G., Ojo, R., Woldesenbet, S., Hutchinson, D.H., Kubena, L.F. Poult. Sci. (1993) [Pubmed]
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