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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Sec15  -  Sec15 ortholog (S. cerevisiae)

Drosophila melanogaster

Synonyms: 3R41, CG7034, Dmel\CG7034, Exocyst complex component 6, Exocyst complex component Sec15, ...
 
 
 
 
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High impact information on sec15

  • While Sec15p binds Sec4-GTP on the vesicle, other subunits bind Rho GTPases on the plasma membrane, thus tethering vesicles to exocytic sites [1].
  • Sec15p, a subunit of the octameric exocyst tethering complex and an effector of Sec4p, binds to Sec2p on secretory vesicles, displacing Ypt32p [1].

References

  1. Interactions between Rabs, tethers, SNAREs and their regulators in exocytosis. Novick, P., Medkova, M., Dong, G., Hutagalung, A., Reinisch, K., Grosshans, B. Biochem. Soc. Trans. (2006) [Pubmed]
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