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Gene Review

ro  -  rough

Drosophila melanogaster

Synonyms: CG6348, DROROUGH, Dmel\CG6348, Homeobox protein rough, Ro
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High impact information on ro

  • rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye [1].
  • We also identified an enhancer trap line that exhibits altered morphogenetic furrow expression in a ro mutant background [2].
  • To identify the transcriptional targets through which ro acts to specify the R2/R5 neuronal sub-type, we screened enhancer trap lines expressed in developing photoreceptors for those whose expression patterns were altered when ro function was inactivated [2].
  • Finally, we have molecularly characterized an enhancer trap line, AE33, that was identified in earlier screens as a target of both ro and gl (freeman et al., 1992; Treisman and Rubin, 1996) [2].
  • In this way we identified two potential ro targets, which are also targets of the zinc finger transcription factor glass (gl) [2].

Anatomical context of ro


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