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Gene Review

Hmu  -  Hemomucin

Drosophila melanogaster

Synonyms: CG3373, Dmel\CG3373, RRM5, Rbp5, SPH210, ...
 
 
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High impact information on Hmu

  • Helix pomatia lectin, an inducer of Drosophila immune response, binds to hemomucin, a novel surface mucin [1].
  • Surprisingly, in contrast to our observation in cell lines, PNA staining of hemomucin was not observed in late third larval and pupal stages, which are known to produce high ecdysone titers [2].
  • Changes in glycosylation during Drosophila development. The influence of ecdysone on hemomucin isoforms [2].
  • The only organ, in which significant amounts of the 105 form were detected, were the ovaries, where hemomucin is produced in follicle cells during the late phase of oogenesis and subsequently incorporated into the chorion [2].

References

  1. Helix pomatia lectin, an inducer of Drosophila immune response, binds to hemomucin, a novel surface mucin. Theopold, U., Samakovlis, C., Erdjument-Bromage, H., Dillon, N., Axelsson, B., Schmidt, O., Tempst, P., Hultmark, D. J. Biol. Chem. (1996) [Pubmed]
  2. Changes in glycosylation during Drosophila development. The influence of ecdysone on hemomucin isoforms. Theopold, U., Dorian, C., Schmidt, O. Insect Biochem. Mol. Biol. (2001) [Pubmed]
 
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