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Gene Review

Slip1  -  CG1783 gene product from transcript CG1783-RA

Drosophila melanogaster

Synonyms: CG1783, Dmel\CG1783, Slo-interacting protein 1, dSLIP1
 
 
 
 
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High impact information on Slip1

  • The dSLIP1 and dSlo mRNAs are expressed coincidently throughout the Drosophila nervous system, the two proteins interact in vitro, and they may be coimmunoprecipitated from transfected cells [1].
  • Single-channel recordings and immunostaining of transfected tissue culture cells suggest that dSLIP1 selectively reduces Slo BK currents by reducing the number of BK channels in the plasma membrane [1].

References

  1. dSLo interacting protein 1, a novel protein that interacts with large-conductance calcium-activated potassium channels. Xia, X., Hirschberg, B., Smolik, S., Forte, M., Adelman, J.P. J. Neurosci. (1998) [Pubmed]
 
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