Gene Review:
Ag5r2 - Antigen 5-related 2
Drosophila melanogaster
Synonyms:
Agr2, CG9540, Dmel\CG9540
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High impact information on Ag5r2
- The protein encoded by Agr2 has 48% identity and 61% similarity to that encoded by Agr [1].
- As embryogenesis proceeds, Agr2 expression expands to form a domain located just posterior to the third midgut constriction [1].
- Transcription of Agr2 is initiated in the embryo within the midgut epithelium near the site where the third midgut constriction will form [1].
- The Agr2 gene was localized to region 12F of the X chromosome and probably lies near the Agr gene [1].
- The proteins encoded by Agr and Agr2 both belong to the CAP family of proteins, which include the mammalian Cysteine-rich secretory proteins, wasp venom Antigen 5 proteins, and plant group 1 Pathogenesis-related proteins [1].
References
- Sequence and expression of Drosophila Antigen 5-related 2, a new member of the CAP gene family. Megraw, T., Kaufman, T.C., Kovalick, G.E. Gene (1998) [Pubmed]
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