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Gene Review:

titf1 - homeobox transcription factor TTF1

Ciona intestinalis

Synonyms: Ci-TTF1, TTF1

Murphy, M.B. et al., Sasaki, A. et al.

Sasaki, Miyamoto, Satou, Satoh, Ogasawara,

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High impact information on titf1

We demonstrate the ability of aptamers that recognize thyroid transcription factor 1 (TTF1) to bind their target protein with high affinity and specificity, and detail their uses in a number of assays [1].
Ci-Ends11 showed an expression pattern similar to that of Ciona TTF-1, which encodes a thyroid-related transcription factor [2].

Analytical, diagnostic and therapeutic context of titf1

The TTF1 aptamers were characterized using surface plasmon resonance, and shown to be useful for enzyme-linked assays, western blots and affinity purification [1].

References

An improved method for the in vitro evolution of aptamers and applications in protein detection and purification. Murphy, M.B., Fuller, S.T., Richardson, P.M., Doyle, S.A. Nucleic Acids Res. (2003) [Pubmed]
Novel endostyle-specific genes in the ascidian Ciona intestinalis. Sasaki, A., Miyamoto, Y., Satou, Y., Satoh, N., Ogasawara, M. Zool. Sci. (2003) [Pubmed]

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