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Gene Review: 

Nup214  -  Nucleoporin 214kD

Drosophila melanogaster

Synonyms: 214 kDa nucleoporin, CAN, CAN/Nup214, CG3820, DCAN, ...
 
 
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High impact information on Nup214

 

Anatomical context of Nup214

  • Overexpression experiments indicated that Nup214 alone attracts a fraction of CRM1 to the nuclear envelope but does not interfere with NES-GFP export [2].
 

Physical interactions of Nup214

References

  1. The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export. Roth, P., Xylourgidis, N., Sabri, N., Uv, A., Fornerod, M., Samakovlis, C. J. Cell Biol. (2003) [Pubmed]
  2. The nucleoporin Nup214 sequesters CRM1 at the nuclear rim and modulates NF{kappa}B activation in Drosophila. Xylourgidis, N., Roth, P., Sabri, N., Tsarouhas, V., Samakovlis, C. J. Cell. Sci. (2006) [Pubmed]
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