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Copb2  -  coatomer protein complex, subunit beta 2...

Mus musculus

Synonyms: AI256832, Beta'-COP, Beta'-coat protein, Coatomer subunit beta', p102
 
 
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Disease relevance of Copb2

  • The recombinant plasmid p102 based on pBR322 carrying approximately equal to 50% of the replicator proximal early region of simian virus 40 (SV40) DNA, including the viral origin of replication, has been constructed [1].
  • No modulation of cell surface p102 antigen by monoclonal antibody 19-24 was observed in human fibrosarcoma cells [2].
  • Partial proteolytic digestion of p98 and p102 with Staphylococcus aureus V8 and chymotrypsin yielded a series of identical peptides, indicating that the two polypeptides are structurally related [3].
  • Therefore, we studied the in vitro expression of sarcoma-associated antigens p102 and p200 in the G, S, and G2/M phases of sarcoma cell lines [4].
 

High impact information on Copb2

  • A high level of p102 cosegregated with resistance to MVMp in cell hybrids between normal human and transformed mouse fibroblasts [5].
  • FISH analyses assigned the beta'-COP gene Copb2 to mouse Chromosome 9, region E3-F1 [6].
  • In an immunological screening of a mouse testicular cDNA library with a human CREST serum we isolated five overlapping cDNA clones encoding the mouse homolog of a Golgi coatomer complex protein (accession number AF043120), designated beta'-COP in bovine and p102 in humans [6].

References

 
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