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Gene Review

TBP  -  TATA box binding protein

Bos taurus

 
 
 
 
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High impact information on LOC516578

  • Here we show that overexpression of the human, but not yeast, TATA box binding protein (TBP) in transfection experiments overcomes this block and enables E2 to activate a minimal TATA box-containing promoter [1].
  • In contrast, minimal promoters that contain an initiator element in addition to a TATA box are efficiently activated by E2 on its own and this activation is only moderately enhanced by TBP overexpression [1].

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