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Gene Review

Rif1  -  Rap1 interacting factor 1 homolog (yeast)

Mus musculus

Synonyms: 5730435J01Rik, 6530403D07Rik, AU016181, AW549474, D2Ertd145e, ...
 
 
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Disease relevance of Rif1

 

High impact information on Rif1

  • Identification and characterisation of mRif1: a mouse telomere-associated protein highly expressed in germ cells and embryo-derived pluripotent stem cells [2].
  • Furthermore, we show that mRif1 physically interacts with the telomere-associated protein mTrf2 and can be cross-linked to telomeric repeat DNA in mouse embryonic stem cells. mRif1 may be involved in the maintenance of telomere length or pluripotency in the germline and during early mouse development [2].

References

 
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