Disease relevance of FTS

• To evaluate the respective roles of nutritional deficiency, infection, and zinc in the alteration of thymic function, we measured the amounts of thymulin (facteur thymic serique, or FTS) and of Zn in the thymus glands of 58 Senegalese children who died in various stages of malnutrition [1].
• The effect of serum thymic factor (FTS) administration in bovine immunodeficiency-like virus (BIV)-infected calves and rabbits was examined [2].

High impact information on FTS

• In contrast, preincubation with thymulin (serum thymic factor (FTS) plus ZnCl2), which shares several physicochemical properties with SDIP, significantly improved the ability of lymphoid cells to induce lethal GVHR [3].
• Thymic hormone containing cells. III. Evidence for a feed-back regulation of the secretion of the serum thymic factor (FTS) by thymic epithelial cells [4].
• The serum thymic factor (FTS). Chemical and biological aspects [5].
• After FTS administration, however, no delay of antibody responses against foreign proteins was observed in BIV-infected calves [2].
• Though the chemiluminescence (CL) responses of macrophages in BIV-infected calves were significantly depressed (p < 0.05), FTS administration resulted in the recovery of the CL responses in the BIV-infected calves comparable to those in the control calves [2].

Chemical compound and disease context of FTS

• Effect of administration of serum thymic factor (FTS) in calves and rabbits infected with bovine immunodeficiency-like virus [2].

Associations of FTS with chemical compounds

• To measure the FTS content in the serum, a serum sample was pretreated with 10% trichloroacetic acid and then with ethanol for removal of serum proteins [6].

Analytical, diagnostic and therapeutic context of FTS

• Conversely, long term elimination of FTS from peripheral blood caused a great increase in the thymic intracellular content of FTS, as evidenced by the higher number of FTS containing cells observed with immunofluorescence [4].
• Soluble antigens from Besnoitia besnoiti cell culture-grown endozoites, obtained either by hypotonic lysis or by freeze-thawing and ultrasonication (FTS) of the organisms, were detected by the agar gel immunodiffusion method [7].
• Radioimmunoassay of serum thymic factor (FTS) [6].

References